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Knockout validation of LAMP2A antibodies for immunostaining in human cancer cells

LAMP2A is the rate-limiting factor of chaperone-mediated autophagy (CMA), a unique selective protein degradative pathway. To date LAMP2A antibodies are not knockout (KO)-validated in human cells. We have recently generated human isoform-specific LAMP2A KO cells, and here we assessed the specificity...

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Detalles Bibliográficos
Autores principales: Zhou, Xun, Shirokova, Vera, Kaminskyy, Vitaliy O., Berenger, Eva, Kochetkova, Elena, Norberg, Erik, Genander, Maria, Vakifahmetoglu-Norberg, Helin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392744/
https://www.ncbi.nlm.nih.gov/pubmed/37194363
http://dx.doi.org/10.1080/15548627.2023.2213515