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Histone deacetylase 3 regulates microglial function through histone deacetylation

As the primary innate immune cells of the brain, microglia respond to damage and disease through pro-inflammatory release of cytokines and neuroinflammatory molecules. Histone acetylation is an activating transcriptional mark that regulates inflammatory gene expression. Inhibition of histone deacety...

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Detalles Bibliográficos
Autores principales: Meleady, Laura, Towriss, Morgan, Kim, Jennifer, Bacarac, Vince, Dang, Vivien, Rowland, Megan E., Ciernia, Annie Vogel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392760/
https://www.ncbi.nlm.nih.gov/pubmed/37506371
http://dx.doi.org/10.1080/15592294.2023.2241008