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The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles

N6-methyladenosine (m6A), the most abundant mRNA modification, is deposited in mammals/insects/plants by m6A methyltransferase complexes (MTC) comprising a catalytic subunit and at least five additional proteins. The yeast MTC is critical for meiosis and was known to comprise three proteins, of whic...

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Detalles Bibliográficos
Autores principales: Ensinck, Imke, Maman, Alexander, Albihlal, Waleed S, Lassandro, Michelangelo, Salzano, Giulia, Sideri, Theodora, Howell, Steven A, Calvani, Enrica, Patel, Harshil, Bushkin, Guy, Ralser, Markus, Snijders, Ambrosius P, Skehel, Mark, Casañal, Ana, Schwartz, Schraga, van Werven, Folkert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393049/
https://www.ncbi.nlm.nih.gov/pubmed/37490041
http://dx.doi.org/10.7554/eLife.87860