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Regulatory roles of an atypical ubiquitin ligase UBE2O in orphans of multiprotein complexes for degradation

UBE2O as an atypical ubiquitin-conjugating enzyme possesses an E2–E3 hybrid enzyme activity. It can regulate substrate levels or transcriptional activities by cooperating with other E3 ubiquitin ligases or forming homomeric complexes displaying intrinsic E2 and E3 activities. UBE2O controls the qual...

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Detalles Bibliográficos
Autores principales: LV, Yi, XING, Feiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific and Technological Research Council of Turkey (TUBITAK) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393103/
https://www.ncbi.nlm.nih.gov/pubmed/37533513
http://dx.doi.org/10.3906/biy-2106-63