Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants

PTEN is a major tumor suppressor gene frequently mutated in human tumors, and germline PTEN gene mutations are the molecular diagnostic of PTEN Hamartoma Tumor Syndrome (PHTS), a heterogeneous disorder that manifests with multiple hamartomas, cancer predisposition, and neurodevelopmental alterations...

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Detalles Bibliográficos
Autores principales: Torices, Leire, Nunes-Xavier, Caroline E., López, José I., Pulido, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393154/
https://www.ncbi.nlm.nih.gov/pubmed/37527256
http://dx.doi.org/10.1371/journal.pone.0289369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393154/
https://www.ncbi.nlm.nih.gov/pubmed/37527256
http://dx.doi.org/10.1371/journal.pone.0289369

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