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Gene signature discovery and systematic validation across diverse clinical cohorts for TB prognosis and response to treatment

While blood gene signatures have shown promise in tuberculosis (TB) diagnosis and treatment monitoring, most signatures derived from a single cohort may be insufficient to capture TB heterogeneity in populations and individuals. Here we report a new generalized approach combining a network-based met...

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Detalles Bibliográficos
Autores principales: Vargas, Roger, Abbott, Liam, Bower, Daniel, Frahm, Nicole, Shaffer, Mike, Yu, Wen-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393163/
https://www.ncbi.nlm.nih.gov/pubmed/37471455
http://dx.doi.org/10.1371/journal.pcbi.1010770