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Evolutionary conservation of the structure and function of meiotic Rec114−Mei4 and Mer2 complexes

Meiosis-specific Rec114−Mei4 and Mer2 complexes are thought to enable Spo11-mediated DNA double-strand break (DSB) formation through a mechanism that involves DNA-dependent condensation. However, the structure, molecular properties, and evolutionary conservation of Rec114−Mei4 and Mer2 are unclear....

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Detalles Bibliográficos
Autores principales: Daccache, Dima, De Jonge, Emma, Liloku, Pascaline, Mechleb, Karen, Haddad, Marita, Corthaut, Sam, Sterckx, Yann G.-J., Volkov, Alexander N., Claeys Bouuaert, Corentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393190/
https://www.ncbi.nlm.nih.gov/pubmed/37442581
http://dx.doi.org/10.1101/gad.350462.123