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Multiancestry sex-stratified genomic associations with HIV viral load and controller status from the ICGH

Biological sex and host genetics influence HIV pathogenesis. Females have a higher likelihood of spontaneous viral control and lower set point viral load (spVL). No prior studies have assessed sex-specific genetics of HIV. To address this, we performed a sex-stratified genome-wide association study...

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Detalles Bibliográficos
Autores principales: Vergara, Candelaria, Tuff, Jeffrey F., Fellay, Jacques, Duggal, Priya, Scully, Eileen P., McLaren, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393222/
https://www.ncbi.nlm.nih.gov/pubmed/37097752
http://dx.doi.org/10.1172/jci.insight.170068