Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling

Previous studies implicate extracellular adenosine signaling in attenuating myocardial ischemia and reperfusion injury (IRI). This extracellular adenosine signaling is terminated by its uptake into cells by equilibrative nucleoside transporters (ENTs). Thus, we hypothesized that targeting ENTs would...

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Detalles Bibliográficos
Autores principales: Ruan, Wei, Li, Jiwen, Choi, Seungwon, Ma, Xinxin, Liang, Yafen, Nair, Ragini, Yuan, Xiaoyi, Mills, Tingting W., Eltzschig, Holger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393224/
https://www.ncbi.nlm.nih.gov/pubmed/37288658
http://dx.doi.org/10.1172/jci.insight.166011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393224/
https://www.ncbi.nlm.nih.gov/pubmed/37288658
http://dx.doi.org/10.1172/jci.insight.166011

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