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Facial neuromuscular junctions and brainstem nuclei are the target of tetanus neurotoxin in cephalic tetanus

Cephalic tetanus (CT) is a severe form of tetanus that follows head wounds and the intoxication of cranial nerves by tetanus neurotoxin (TeNT). Hallmarks of CT are cerebral palsy, which anticipates the spastic paralysis of tetanus, and rapid evolution of cardiorespiratory deficit even without genera...

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Detalles Bibliográficos
Autores principales: Fabris, Federico, Varani, Stefano, Tonellato, Marika, Matak, Ivica, Šoštarić, Petra, Meglić, Patrik, Caleo, Matteo, Megighian, Aram, Rossetto, Ornella, Montecucco, Cesare, Pirazzini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393225/
https://www.ncbi.nlm.nih.gov/pubmed/37159261
http://dx.doi.org/10.1172/jci.insight.166978