CLUH functions as a negative regulator of inflammation in human macrophages and determines ulcerative colitis pathogenesis

Altered mitochondrial function without a well-defined cause has been documented in patients with ulcerative colitis (UC). In our efforts to understand UC pathogenesis, we observed reduced expression of clustered mitochondrial homolog (CLUH) only in the active UC tissues compared with the unaffected...

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Detalles Bibliográficos
Autores principales: Khan, Shaziya, Raj, Desh, Sahu, Shikha, Naseer, Anam, Singh, Nishakumari C., Kumari, Sunaina, Ishteyaque, Sharmeen, Sharma, Jyotsna, Lakra, Promila, Mugale, Madhav N., Trivedi, Arun Kumar, Srivastava, Mrigank, Chandra, Tulika, Bhosale, Vivek, Barthwal, Manoj Kumar, Gupta, Shashi Kumar, Mitra, Kalyan, Nazir, Aamir, Ghoshal, Uday C., Lahiri, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393232/
https://www.ncbi.nlm.nih.gov/pubmed/37140992
http://dx.doi.org/10.1172/jci.insight.161096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393232/
https://www.ncbi.nlm.nih.gov/pubmed/37140992
http://dx.doi.org/10.1172/jci.insight.161096

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