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CLUH functions as a negative regulator of inflammation in human macrophages and determines ulcerative colitis pathogenesis
Altered mitochondrial function without a well-defined cause has been documented in patients with ulcerative colitis (UC). In our efforts to understand UC pathogenesis, we observed reduced expression of clustered mitochondrial homolog (CLUH) only in the active UC tissues compared with the unaffected...
Autores principales: | Khan, Shaziya, Raj, Desh, Sahu, Shikha, Naseer, Anam, Singh, Nishakumari C., Kumari, Sunaina, Ishteyaque, Sharmeen, Sharma, Jyotsna, Lakra, Promila, Mugale, Madhav N., Trivedi, Arun Kumar, Srivastava, Mrigank, Chandra, Tulika, Bhosale, Vivek, Barthwal, Manoj Kumar, Gupta, Shashi Kumar, Mitra, Kalyan, Nazir, Aamir, Ghoshal, Uday C., Lahiri, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393232/ https://www.ncbi.nlm.nih.gov/pubmed/37140992 http://dx.doi.org/10.1172/jci.insight.161096 |
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