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Age-related and amyloid-beta-independent tau deposition and its downstream effects

Amyloid-β (Aβ) is hypothesized to facilitate the spread of tau pathology beyond the medial temporal lobe. However, there is evidence that, independently of Aβ, age-related tau pathology might be present outside of the medial temporal lobe. We therefore aimed to study age-related Aβ-independent tau d...

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Detalles Bibliográficos
Autores principales: Wuestefeld, Anika, Pichet Binette, Alexa, Berron, David, Spotorno, Nicola, van Westen, Danielle, Stomrud, Erik, Mattsson-Carlgren, Niklas, Strandberg, Olof, Smith, Ruben, Palmqvist, Sebastian, Glenn, Trevor, Moes, Svenja, Honer, Michael, Arfanakis, Konstantinos, Barnes, Lisa L, Bennett, David A, Schneider, Julie A, Wisse, Laura E M, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393402/
https://www.ncbi.nlm.nih.gov/pubmed/37082959
http://dx.doi.org/10.1093/brain/awad135