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Nanopore sequencing of PCR products enables multicopy gene family reconstruction

The importance of gene amplifications in evolution is more and more recognized. Yet, tools to study multi-copy gene families are still scarce, and many such families are overlooked using common sequencing methods. Haplotype reconstruction is even harder for polymorphic multi-copy gene families. Here...

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Detalles Bibliográficos
Autores principales: Namias, Alice, Sahlin, Kristoffer, Makoundou, Patrick, Bonnici, Iago, Sicard, Mathieu, Belkhir, Khalid, Weill, Mylène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393513/
https://www.ncbi.nlm.nih.gov/pubmed/37533804
http://dx.doi.org/10.1016/j.csbj.2023.07.012