A celastrol-based nanodrug with reduced hepatotoxicity for primary and metastatic cancer treatment

BACKGROUND: Cancer is the world's leading cause of death and a key hindrance to extending life expectancy. Celastrol, a bioactive compound derived from Tripterygium wilfordii, has been shown to have excellent antitumor activity, but its poor solubility and severe organ toxicity side effects hav...

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Detalles Bibliográficos
Autores principales: Zhou, Min, Liao, Jiaxing, Lai, Wenjing, Xu, Rufu, Liu, Wuyi, Xie, Dandan, Wang, Fengling, Zhang, Zhe, Huang, Jingbin, Zhang, Rong, Li, Guobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393547/
https://www.ncbi.nlm.nih.gov/pubmed/37480625
http://dx.doi.org/10.1016/j.ebiom.2023.104724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393547/
https://www.ncbi.nlm.nih.gov/pubmed/37480625
http://dx.doi.org/10.1016/j.ebiom.2023.104724

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