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A celastrol-based nanodrug with reduced hepatotoxicity for primary and metastatic cancer treatment
BACKGROUND: Cancer is the world's leading cause of death and a key hindrance to extending life expectancy. Celastrol, a bioactive compound derived from Tripterygium wilfordii, has been shown to have excellent antitumor activity, but its poor solubility and severe organ toxicity side effects hav...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393547/ https://www.ncbi.nlm.nih.gov/pubmed/37480625 http://dx.doi.org/10.1016/j.ebiom.2023.104724 |