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Umbilical mesenchymal stem cell-derived exosomes promote spinal cord functional recovery through the miR-146b/TLR4 -mediated NF-κB p65 signaling pathway in rats

Spinal cord injury (SCI) is an incurable central nervous system impairment that lack of efficient treatment. Exosomes derived from mesenchymal stem cells (MSCs) are widely applied in disease treatment. This work aimed to determine the promising therapeutic effects of MSC-derived exosomal miRNA146b o...

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Detalles Bibliográficos
Autores principales: Wang, Xiujuan, Yang, Ying, Li, Wei, Hao, MingYuan, Xu, YongSheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393557/
https://www.ncbi.nlm.nih.gov/pubmed/37534324
http://dx.doi.org/10.1016/j.bbrep.2023.101497