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Multi-scale spatial modeling of immune cell distributions enables survival prediction in primary central nervous system lymphoma

To understand the clinical significance of the tumor microenvironment (TME), it is essential to study the interactions between malignant and non-malignant cells in clinical specimens. Here, we established a computational framework for a multiplex imaging system to comprehensively characterize spatia...

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Detalles Bibliográficos
Autores principales: Roemer, Margaretha G.M., van de Brug, Tim, Bosch, Erik, Berry, Daniella, Hijmering, Nathalie, Stathi, Phylicia, Weijers, Karin, Doorduijn, Jeannette, Bromberg, Jacoline, van de Wiel, Mark, Ylstra, Bauke, de Jong, Daphne, Kim, Yongsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393746/
https://www.ncbi.nlm.nih.gov/pubmed/37539043
http://dx.doi.org/10.1016/j.isci.2023.107331