Group size planning for breedings of gene-modified mice and other organisms following Mendelian inheritance

Colony management of gene-modified animals is time-consuming, costly and affected by random events related to Mendelian genetics, fertility and litter size. Careful planning is mandatory to ensure successful outcomes using the least number of animals, hence adhering to the 3R principles of animal we...

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Detalles Bibliográficos
Autores principales: Milchevskaya, Vladislava, Bugnon, Philippe, ten Buren, Emiel B. J., Vanhecke, Dominique, Brand, Frank, Tresch, Achim, Buch, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393774/
https://www.ncbi.nlm.nih.gov/pubmed/37488410
http://dx.doi.org/10.1038/s41684-023-01213-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393774/
https://www.ncbi.nlm.nih.gov/pubmed/37488410
http://dx.doi.org/10.1038/s41684-023-01213-1

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