Have you tried turning it off and on again? Oscillating selection to enhance fitness-landscape traversal in adaptive laboratory evolution experiments

Adaptive Laboratory Evolution (ALE) is a powerful tool for engineering and understanding microbial physiology. ALE relies on the selection and enrichment of mutations that enable survival or faster growth under a selective condition imposed by the experimental setup. Phenotypic fitness landscapes ar...

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Detalles Bibliográficos
Autores principales: Carpenter, Alexander C., Feist, Adam M., Harrison, Fergus S.M., Paulsen, Ian T., Williams, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393799/
https://www.ncbi.nlm.nih.gov/pubmed/37538933
http://dx.doi.org/10.1016/j.mec.2023.e00227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393799/
https://www.ncbi.nlm.nih.gov/pubmed/37538933
http://dx.doi.org/10.1016/j.mec.2023.e00227

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