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Have you tried turning it off and on again? Oscillating selection to enhance fitness-landscape traversal in adaptive laboratory evolution experiments
Adaptive Laboratory Evolution (ALE) is a powerful tool for engineering and understanding microbial physiology. ALE relies on the selection and enrichment of mutations that enable survival or faster growth under a selective condition imposed by the experimental setup. Phenotypic fitness landscapes ar...
Autores principales: | Carpenter, Alexander C., Feist, Adam M., Harrison, Fergus S.M., Paulsen, Ian T., Williams, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393799/ https://www.ncbi.nlm.nih.gov/pubmed/37538933 http://dx.doi.org/10.1016/j.mec.2023.e00227 |
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