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Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma

Extranodal natural killer/T cell lymphoma, nasal type (ENKTL) is an aggressive lymphoid malignancy with a poor prognosis and lacks standard treatment. Targeted therapies are urgently needed. Here we systematically investigated the druggable mechanisms through chemogenomic screening and identified th...

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Detalles Bibliográficos
Autores principales: Liu, Chuanxu, Ding, Xinyu, Li, Gaoyang, Zhang, Youping, Shao, Yubao, Liu, Linyi, Zhang, Wenhao, Ma, Yujie, Guan, Wenbin, Wang, Lifeng, Xu, Zhongli, Chang, YungTing, Zhang, Yongqiang, Jiang, Biao, Yin, Qianqian, Tao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393801/
https://www.ncbi.nlm.nih.gov/pubmed/37539026
http://dx.doi.org/10.1016/j.isci.2023.107369