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Assessing the in vivo efficacy of rational antibiotics and combinations against difficult-to-treat Pseudomonas aeruginosa producing GES β-lactamases

OBJECTIVES: We evaluated the in vivo efficacy of human-simulated regimens (HSRs) of cefiderocol, ceftazidime/avibactam, meropenem and ceftazidime/avibactam/meropenem combination against Guiana-extended spectrum (GES)-producing Pseudomonas aeruginosa isolates. METHODS: Eighteen P. aeruginosa isolates...

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Detalles Bibliográficos
Autores principales: Abouelhassan, Yasmeen, Gill, Christian M, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393871/
https://www.ncbi.nlm.nih.gov/pubmed/37357368
http://dx.doi.org/10.1093/jac/dkad098