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Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites

Invasion of red blood cells (RBCs) by Plasmodium merozoites is critical to their continued survival within the host. Two major protein families, the Duffy binding-like proteins (DBPs/EBAs) and the reticulocyte binding like proteins (RBLs/RHs) have been studied extensively in P. falciparum and are hy...

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Detalles Bibliográficos
Autores principales: Hart, Melissa N., Mohring, Franziska, DonVito, Sophia M., Thomas, James A., Muller-Sienerth, Nicole, Wright, Gavin J., Knuepfer, Ellen, Saibil, Helen R., Moon, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393984/
https://www.ncbi.nlm.nih.gov/pubmed/37528099
http://dx.doi.org/10.1038/s41467-023-40357-z