Enhancement of the SESN2-SHP cascade by melatonin ameliorates hepatic gluconeogenesis by inhibiting the CRBN-BTG2-CREBH signaling pathway

Melatonin is involved in the regulation of various biological functions. Here, we explored a novel molecular mechanism by which the melatonin-induced sestrin2 (SESN2)-small heterodimer partner (SHP) signaling pathway protects against fasting- and diabetes-mediated hepatic glucose metabolism. Various...

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Detalles Bibliográficos
Autores principales: An, Seungwon, Nedumaran, Balachandar, Koh, Hong, Joo, Dong Jin, Lee, Hyungjo, Park, Chul-Seung, Harris, Robert A., Shin, Keong Sub, Djalilian, Ali R., Kim, Yong Deuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393991/
https://www.ncbi.nlm.nih.gov/pubmed/37488285
http://dx.doi.org/10.1038/s12276-023-01040-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393991/
https://www.ncbi.nlm.nih.gov/pubmed/37488285
http://dx.doi.org/10.1038/s12276-023-01040-x

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