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SOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction

Lysophosphatidic acid receptor 4 (LPAR4) exhibits transient expression at the cardiac progenitor stage during pluripotent stem cell (PSC)-derived cardiac differentiation. Using RNA sequencing, promoter analyses, and a loss-of-function study in human PSCs, we discovered that SRY-box transcription fac...

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Detalles Bibliográficos
Autores principales: Lee, Jin-Woo, Lee, Choon-Soo, Son, HyunJu, Lee, Jaewon, Kang, Minjun, Chai, Jinho, Cho, Hyun-Jai, Kim, Hyo-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394006/
https://www.ncbi.nlm.nih.gov/pubmed/37394586
http://dx.doi.org/10.1038/s12276-023-01025-w