Cargando…
SOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction
Lysophosphatidic acid receptor 4 (LPAR4) exhibits transient expression at the cardiac progenitor stage during pluripotent stem cell (PSC)-derived cardiac differentiation. Using RNA sequencing, promoter analyses, and a loss-of-function study in human PSCs, we discovered that SRY-box transcription fac...
Autores principales: | Lee, Jin-Woo, Lee, Choon-Soo, Son, HyunJu, Lee, Jaewon, Kang, Minjun, Chai, Jinho, Cho, Hyun-Jai, Kim, Hyo-Soo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394006/ https://www.ncbi.nlm.nih.gov/pubmed/37394586 http://dx.doi.org/10.1038/s12276-023-01025-w |
Ejemplares similares
-
Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK
por: Lee, Choon-Soo, et al.
Publicado: (2021) -
The G Protein-Coupled Receptor Latrophilin-2, A Marker for Heart Development, Induces Myocardial Repair After Infarction
por: Lee, Choon-Soo, et al.
Publicado: (2022) -
Lysophosphatidic Acid Receptor 4 Is Transiently Expressed during Cardiac Differentiation and Critical for Repair of the Damaged Heart
por: Lee, Jin-Woo, et al.
Publicado: (2021) -
Cardiovascular Regeneration via Stem Cells and Direct Reprogramming: A Review
por: Lee, Choon-Soo, et al.
Publicado: (2022) -
Designing Dual Inhibitors of Autotaxin-LPAR GPCR Axis
por: Banerjee, Souvik, et al.
Publicado: (2022)