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Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4

To date, there is no effective therapy for pathological cardiac hypertrophy, which can ultimately lead to heart failure. Bellidifolin (BEL) is an active xanthone component of Gentianella acuta (G. acuta) with a protective function for the heart. However, the role and mechanism of BEL action in cardi...

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Detalles Bibliográficos
Autores principales: Zhou, Dingyan, Liu, Weizhe, Zhang, Juanjuan, Dong, Yucui, Wu, Jiangli, Zhang, Yu, Dai, Cheng, Zhang, Tingting, Yang, Gaoshan, Zhang, Yue, Li, Aiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394041/
https://www.ncbi.nlm.nih.gov/pubmed/37528096
http://dx.doi.org/10.1038/s41420-023-01563-2