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Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4
To date, there is no effective therapy for pathological cardiac hypertrophy, which can ultimately lead to heart failure. Bellidifolin (BEL) is an active xanthone component of Gentianella acuta (G. acuta) with a protective function for the heart. However, the role and mechanism of BEL action in cardi...
Autores principales: | Zhou, Dingyan, Liu, Weizhe, Zhang, Juanjuan, Dong, Yucui, Wu, Jiangli, Zhang, Yu, Dai, Cheng, Zhang, Tingting, Yang, Gaoshan, Zhang, Yue, Li, Aiying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394041/ https://www.ncbi.nlm.nih.gov/pubmed/37528096 http://dx.doi.org/10.1038/s41420-023-01563-2 |
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