Cargando…

Inhibition of autotaxin alleviates pathological features of hepatic encephalopathy at the level of gut–liver–brain axis: an experimental and bioinformatic study

There is accumulating evidence that the circulatory levels of autotaxin (ATX) and lysophosphatidic acid (LPA) are increased in patients with severe liver disease. However, the potential role of the ATX-LPA axis in hepatic encephalopathy (HE) remains unclear. Our study aimed to investigate the role o...

Descripción completa

Detalles Bibliográficos
Autores principales: Sepehrinezhad, Ali, Shahbazi, Ali, Joghataei, Mohammad Taghi, Larsen, Fin Stolze, Sahab Negah, Sajad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394058/
https://www.ncbi.nlm.nih.gov/pubmed/37528089
http://dx.doi.org/10.1038/s41419-023-06022-5