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Comparison of infection and human immune responses of two SARS-CoV-2 strains in a humanized hACE2 NIKO mouse model

The COVID-19 pandemic has sickened millions, cost lives and has devastated the global economy. Various animal models for experimental infection with SARS-CoV-2 have played a key role in many aspects of COVID-19 research. Here, we describe a humanized hACE2 (adenovirus expressing hACE2) NOD-SCID IL2R...

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Detalles Bibliográficos
Autores principales: Yong, Kylie Su Mei, Anderson, Danielle E., Zheng, Adrian Kang Eng, Liu, Min, Tan, Sue Yee, Tan, Wilson Wei Sheng, Chen, Qingfeng, Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394059/
https://www.ncbi.nlm.nih.gov/pubmed/37528224
http://dx.doi.org/10.1038/s41598-023-39628-y