Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation

A large group of hormones are stored as amyloid fibrils in acidic secretion vesicles before they are released into the bloodstream and readopt their functional state. Here, we identify an evolutionarily conserved hexapeptide sequence as the major aggregation-prone region (APR) of gastrointestinal pe...

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Detalles Bibliográficos
Autores principales: Horváth, Dániel, Dürvanger, Zsolt, K. Menyhárd, Dóra, Sulyok-Eiler, Máté, Bencs, Fruzsina, Gyulai, Gergő, Horváth, Péter, Taricska, Nóra, Perczel, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394066/
https://www.ncbi.nlm.nih.gov/pubmed/37528104
http://dx.doi.org/10.1038/s41467-023-40294-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394066/
https://www.ncbi.nlm.nih.gov/pubmed/37528104
http://dx.doi.org/10.1038/s41467-023-40294-x

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