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simCAS: an embedding-based method for simulating single-cell chromatin accessibility sequencing data

MOTIVATION: Single-cell chromatin accessibility sequencing (scCAS) technology provides an epigenomic perspective to characterize gene regulatory mechanisms at single-cell resolution. With an increasing number of computational methods proposed for analyzing scCAS data, a powerful simulation framework...

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Detalles Bibliográficos
Autores principales: Li, Chen, Chen, Xiaoyang, Chen, Shengquan, Jiang, Rui, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394124/
https://www.ncbi.nlm.nih.gov/pubmed/37494428
http://dx.doi.org/10.1093/bioinformatics/btad453