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GPAM mediated lysophosphatidic acid synthesis regulates mitochondrial dynamics in acute myeloid leukemia

Metabolic alterations, especially in the mitochondria, play important roles in several kinds of cancers, including acute myeloid leukemia (AML). However, AML‐specific molecular mechanisms that regulate mitochondrial dynamics remain elusive. Through the metabolite screening comparing CD34(+) AML cell...

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Detalles Bibliográficos
Autores principales: Irifune, Hidetoshi, Kochi, Yu, Miyamoto, Toshihiro, Sakoda, Teppei, Kato, Koji, Kunisaki, Yuya, Akashi, Koichi, Kikushige, Yoshikane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394129/
https://www.ncbi.nlm.nih.gov/pubmed/37197765
http://dx.doi.org/10.1111/cas.15835