Cargando…

Circadian clock protein Bmal1 accelerates acute myeloid leukemia by inhibiting ferroptosis through the EBF3/ALOX15 axis

Acute myeloid leukemia (AML) is a major leukemia with high mortality. Ferroptosis is an important regulator of cancers. However, the role of ferroptosis and its regulatory mechanisms in AML remain largely unknown. In this study, we reported elevated brain and muscle ARNT‐Like protein‐1 (Bmal1) expre...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Dan, Wang, Fenglin, Zhang, Haixia, Chen, Pan, Yang, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394146/
https://www.ncbi.nlm.nih.gov/pubmed/37271497
http://dx.doi.org/10.1111/cas.15875