A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma

Multiple myeloma (MM) is an incurable malignancy of plasma cells. To identify targets for MM immunotherapy, we develop an integrated pipeline based on mass spectrometry analysis of seven MM cell lines and RNA sequencing (RNA-seq) from 900+ patients. Starting from 4,000+ candidates, we identify the m...

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Detalles Bibliográficos
Autores principales: Di Meo, Francesco, Iyer, Anjushree, Akama, Keith, Cheng, Rujin, Yu, Christina, Cesarano, Annamaria, Kurihara, Noriyoshi, Tenshin, Hirofumi, Aljoufi, Arafat, Marino, Silvia, Soni, Rajesh K., Roda, Julie, Sissons, James, Vu, Ly P., Guzman, Monica, Huang, Kun, Laskowski, Tamara, Broxmeyer, Hal E., Roodman, David G., Perna, Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394163/
https://www.ncbi.nlm.nih.gov/pubmed/37467717
http://dx.doi.org/10.1016/j.xcrm.2023.101110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394163/
https://www.ncbi.nlm.nih.gov/pubmed/37467717
http://dx.doi.org/10.1016/j.xcrm.2023.101110

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