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Blood transcriptional correlates of BCG-induced protection against tuberculosis in rhesus macaques

Blood-based correlates of vaccine-induced protection against tuberculosis (TB) are urgently needed. Here, we analyze the blood transcriptome of rhesus macaques immunized with varying doses of intravenous (i.v.) BCG followed by Mycobacterium tuberculosis (Mtb) challenge. We use high-dose i.v. BCG rec...

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Detalles Bibliográficos
Autores principales: Liu, Yiran E., Darrah, Patricia A., Zeppa, Joseph J., Kamath, Megha, Laboune, Farida, Douek, Daniel C., Maiello, Pauline, Roederer, Mario, Flynn, JoAnne L., Seder, Robert A., Khatri, Purvesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394165/
https://www.ncbi.nlm.nih.gov/pubmed/37390827
http://dx.doi.org/10.1016/j.xcrm.2023.101096