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Blood transcriptional correlates of BCG-induced protection against tuberculosis in rhesus macaques
Blood-based correlates of vaccine-induced protection against tuberculosis (TB) are urgently needed. Here, we analyze the blood transcriptome of rhesus macaques immunized with varying doses of intravenous (i.v.) BCG followed by Mycobacterium tuberculosis (Mtb) challenge. We use high-dose i.v. BCG rec...
Autores principales: | Liu, Yiran E., Darrah, Patricia A., Zeppa, Joseph J., Kamath, Megha, Laboune, Farida, Douek, Daniel C., Maiello, Pauline, Roederer, Mario, Flynn, JoAnne L., Seder, Robert A., Khatri, Purvesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394165/ https://www.ncbi.nlm.nih.gov/pubmed/37390827 http://dx.doi.org/10.1016/j.xcrm.2023.101096 |
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