Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity

Type 1 diabetes (T1D) results from autoimmune destruction of β cells. Insufficient availability of biomarkers represents a significant gap in understanding the disease cause and progression. We conduct blinded, two-phase case-control plasma proteomics on the TEDDY study to identify biomarkers predic...

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Detalles Bibliográficos
Autores principales: Nakayasu, Ernesto S., Bramer, Lisa M., Ansong, Charles, Schepmoes, Athena A., Fillmore, Thomas L., Gritsenko, Marina A., Clauss, Therese R., Gao, Yuqian, Piehowski, Paul D., Stanfill, Bryan A., Engel, Dave W., Orton, Daniel J., Moore, Ronald J., Qian, Wei-Jun, Sechi, Salvatore, Frohnert, Brigitte I., Toppari, Jorma, Ziegler, Anette-G., Lernmark, Åke, Hagopian, William, Akolkar, Beena, Smith, Richard D., Rewers, Marian J., Webb-Robertson, Bobbie-Jo M., Metz, Thomas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394168/
https://www.ncbi.nlm.nih.gov/pubmed/37390828
http://dx.doi.org/10.1016/j.xcrm.2023.101093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394168/
https://www.ncbi.nlm.nih.gov/pubmed/37390828
http://dx.doi.org/10.1016/j.xcrm.2023.101093

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