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KMT2C knockout generates ASD-like behaviors in mice

Neurodevelopmental disorders have been associated with genetic mutations that affect cellular function, including chromatin regulation and epigenetic modifications. Recent studies in humans have identified mutations in KMT2C, an enzyme responsible for modifying histone tails and depositing H3K4me1 a...

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Detalles Bibliográficos
Autores principales: Brauer, Bastian, Merino-Veliz, Nicolas, Ahumada-Marchant, Constanza, Arriagada, Gloria, Bustos, Fernando J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394233/
https://www.ncbi.nlm.nih.gov/pubmed/37538398
http://dx.doi.org/10.3389/fcell.2023.1227723