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KMT2C knockout generates ASD-like behaviors in mice
Neurodevelopmental disorders have been associated with genetic mutations that affect cellular function, including chromatin regulation and epigenetic modifications. Recent studies in humans have identified mutations in KMT2C, an enzyme responsible for modifying histone tails and depositing H3K4me1 a...
Autores principales: | Brauer, Bastian, Merino-Veliz, Nicolas, Ahumada-Marchant, Constanza, Arriagada, Gloria, Bustos, Fernando J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394233/ https://www.ncbi.nlm.nih.gov/pubmed/37538398 http://dx.doi.org/10.3389/fcell.2023.1227723 |
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