Mutant HTT does not affect glial development but impairs myelination in the early disease stage

INTRODUCTION: Huntington’s disease (HD) is caused by expanded CAG repeats in the huntingtin gene (HTT) and is characterized by late-onset neurodegeneration that primarily affects the striatum. Several studies have shown that mutant HTT can also affect neuronal development, contributing to the late-o...

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Detalles Bibliográficos
Autores principales: Yang, Sitong, Ma, Jingjing, Zhang, Han, Chen, Laiqiang, Li, Yuxuan, Pan, Mingtian, Zhu, Hongcheng, Liang, Jun, He, Dajian, Li, Shihua, Li, Xiao-Jiang, Guo, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394243/
https://www.ncbi.nlm.nih.gov/pubmed/37539389
http://dx.doi.org/10.3389/fnins.2023.1238306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394243/
https://www.ncbi.nlm.nih.gov/pubmed/37539389
http://dx.doi.org/10.3389/fnins.2023.1238306

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