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Mutant HTT does not affect glial development but impairs myelination in the early disease stage
INTRODUCTION: Huntington’s disease (HD) is caused by expanded CAG repeats in the huntingtin gene (HTT) and is characterized by late-onset neurodegeneration that primarily affects the striatum. Several studies have shown that mutant HTT can also affect neuronal development, contributing to the late-o...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394243/ https://www.ncbi.nlm.nih.gov/pubmed/37539389 http://dx.doi.org/10.3389/fnins.2023.1238306 |