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A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence

Recurrences frequently occur following surgical removal of primary tumors. In many cancers, adjuvant therapies have limited efficacy. Surgery provides access to the tumor microenvironment, creating an opportunity for local therapy, in particular immunotherapy, which can induce local and systemic ant...

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Detalles Bibliográficos
Autores principales: Rwandamuriye, Francois Xavier, Evans, Cameron W., Wylie, Ben, Norret, Marck, Vitali, Breana, Ho, Diwei, Nguyen, Dat, Roper, Ellise A., Wang, Tao, Hepburn, Matt S., Sanderson, Rowan W., Pfirrmann, Maren, Fear, Vanessa S., Forbes, Catherine A., Wyatt, Ken, Ryan, Anne L., Johns, Terrance G., Phillips, Marianne B., Hodder, Rupert, Leslie, Connull, Kennedy, Brendan F., Zemek, Rachael M., Iyer, Killugudi Swaminathan, Lesterhuis, Willem Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394259/
https://www.ncbi.nlm.nih.gov/pubmed/37467718
http://dx.doi.org/10.1016/j.xcrm.2023.101113