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Multimodal immune cell phenotyping in GI biopsies reveals microbiome-related T cell modulations in human GvHD

Acute graft-versus-host disease (aGvHD) is a significant complication after allogeneic hematopoietic stem cell transplantation (aHSCT), but major factors determining disease severity are not well defined yet. By combining multiplexed tissue imaging and single-cell RNA sequencing on gastrointestinal...

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Detalles Bibliográficos
Autores principales: Jarosch, Sebastian, Köhlen, Jan, Ghimire, Sakhila, Orberg, Erik Thiele, Hammel, Monika, Gaag, Doris, Evert, Matthias, Janssen, Klaus-Peter, Hiergeist, Andreas, Gessner, André, Weber, Daniela, Meedt, Elisabeth, Poeck, Hendrik, D’Ippolito, Elvira, Holler, Ernst, Busch, Dirk H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394271/
https://www.ncbi.nlm.nih.gov/pubmed/37467715
http://dx.doi.org/10.1016/j.xcrm.2023.101125