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Multimodal immune cell phenotyping in GI biopsies reveals microbiome-related T cell modulations in human GvHD
Acute graft-versus-host disease (aGvHD) is a significant complication after allogeneic hematopoietic stem cell transplantation (aHSCT), but major factors determining disease severity are not well defined yet. By combining multiplexed tissue imaging and single-cell RNA sequencing on gastrointestinal...
Autores principales: | Jarosch, Sebastian, Köhlen, Jan, Ghimire, Sakhila, Orberg, Erik Thiele, Hammel, Monika, Gaag, Doris, Evert, Matthias, Janssen, Klaus-Peter, Hiergeist, Andreas, Gessner, André, Weber, Daniela, Meedt, Elisabeth, Poeck, Hendrik, D’Ippolito, Elvira, Holler, Ernst, Busch, Dirk H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394271/ https://www.ncbi.nlm.nih.gov/pubmed/37467715 http://dx.doi.org/10.1016/j.xcrm.2023.101125 |
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