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Otoferlin as a multirole Ca(2+) signaling protein: from inner ear synapses to cancer pathways
Humans have six members of the ferlin protein family: dysferlin, myoferlin, otoferlin, fer1L4, fer1L5, and fer1L6. These proteins share common features such as multiple Ca(2+)-binding C2 domains, FerA domains, and membrane anchoring through their single C-terminal transmembrane domain, and are belie...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394277/ https://www.ncbi.nlm.nih.gov/pubmed/37538852 http://dx.doi.org/10.3389/fncel.2023.1197611 |