Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans

BACKGROUND & AIMS: OATP1B3/SLCO1B3 is a human liver-specific transporter for the clearance of endogenous compounds (eg, bile acid [BA]) and xenobiotics. The functional role of OATP1B3 in humans has not been characterized, as SLCO1B3 is poorly conserved among species without mouse orthologs. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Qiong, Zhu, Guanyu, Xu, Ziqian, Zhu, Jinfei, Ouyang, Jiafeng, Tong, Yao, Zhao, Nan, Zhang, Xiaoxun, Cheng, Ying, Zhang, Liangjun, Tan, Ya, Li, Jianwei, Zhang, Chengcheng, Chen, Wensheng, Cai, Shi-Ying, Boyer, James L., Chai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394288/
https://www.ncbi.nlm.nih.gov/pubmed/37146714
http://dx.doi.org/10.1016/j.jcmgh.2023.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394288/
https://www.ncbi.nlm.nih.gov/pubmed/37146714
http://dx.doi.org/10.1016/j.jcmgh.2023.04.007

Ejemplares similares