Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation

Caveolin-1 (CAV1) and CAV3 are membrane-sculpting proteins driving the formation of the plasma membrane (PM) caveolae. Within the PM mosaic environment, caveola assembly is unique as it requires progressive oligomerization of newly synthesized caveolins while trafficking through the biosynthetic-sec...

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Detalles Bibliográficos
Autores principales: Morales-Paytuví, Frederic, Fajardo, Alba, Ruiz-Mirapeix, Carles, Rae, James, Tebar, Francesc, Bosch, Marta, Enrich, Carlos, Collins, Brett M., Parton, Robert G., Pol, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394380/
https://www.ncbi.nlm.nih.gov/pubmed/37526691
http://dx.doi.org/10.1083/jcb.202204020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394380/
https://www.ncbi.nlm.nih.gov/pubmed/37526691
http://dx.doi.org/10.1083/jcb.202204020

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