Cargando…

Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation

Caveolin-1 (CAV1) and CAV3 are membrane-sculpting proteins driving the formation of the plasma membrane (PM) caveolae. Within the PM mosaic environment, caveola assembly is unique as it requires progressive oligomerization of newly synthesized caveolins while trafficking through the biosynthetic-sec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morales-Paytuví, Frederic, Fajardo, Alba, Ruiz-Mirapeix, Carles, Rae, James, Tebar, Francesc, Bosch, Marta, Enrich, Carlos, Collins, Brett M., Parton, Robert G., Pol, Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394380/ https://www.ncbi.nlm.nih.gov/pubmed/37526691 http://dx.doi.org/10.1083/jcb.202204020

Ejemplares similares

Revisiting caveolin trafficking: the end of the caveosome
por: Parton, Robert G., et al.
Publicado: (2010)

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation
por: Herms, Albert, et al.
Publicado: (2015)

Annexin A6-Induced Alterations in Cholesterol Transport and Caveolin Export from the Golgi Complex
por: Cubells, Laia, et al.
Publicado: (2007)

ROCK1 is a novel Rac1 effector to regulate tubular endocytic membrane formation during clathrin-independent endocytosis
por: Soriano-Castell, David, et al.
Publicado: (2017)

Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function
por: Reverter, Meritxell, et al.
Publicado: (2011)

Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains
por: Kassan, Adam, et al.
Publicado: (2013)

The structure of caveolin finally takes shape
por: Parton, Robert G., et al.
Publicado: (2022)

Annexins Bridging the Gap: Novel Roles in Membrane Contact Site Formation
por: Enrich, Carlos, et al.
Publicado: (2022)

Adapt, Recycle, and Move on: Proteostasis and Trafficking Mechanisms in Melanoma
por: Demirsoy, Seyma, et al.
Publicado: (2016)

Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease
por: Tebar, Francesc, et al.
Publicado: (2020)

Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase
por: Cai, Ting, et al.
Publicado: (2008)

Oligomerization of Clostridium perfringens Epsilon Toxin Is Dependent upon Caveolins 1 and 2
por: Fennessey, Christine M., et al.
Publicado: (2012)

A Caveolin Dominant Negative Mutant Associates with Lipid Bodies and Induces Intracellular Cholesterol Imbalance
por: Pol, Albert, et al.
Publicado: (2001)

Impact of Caveolin-Mediated Endocytosis on the Trafficking of HIV within the Colonic Barrier
por: Anwar, Alex, et al.
Publicado: (2022)

Bacteria-Derived Protein Aggregates Contribute to the Disruption of Host Proteostasis
por: Walker, Alyssa C., et al.
Publicado: (2022)

Molecular Characterization of Caveolin Association with the Golgi Complex: Identification of a Cis-Golgi Targeting Domain in the Caveolin Molecule
por: Luetterforst, Robert, et al.
Publicado: (1999)

Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis
por: Bhattachan, Punit, et al.
Publicado: (2019)

Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae
por: Zhou, Yong, et al.
Publicado: (2021)

Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells
por: Meneses-Salas, Elsa, et al.
Publicado: (2019)

Caveolin-3 Associates with Developing T-tubules during Muscle Differentiation
por: Parton, Robert G., et al.
Publicado: (1997)

Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence
por: Sierecki, Emma, et al.
Publicado: (2016)

Alpha 1-Antitrypsin Deficiency: A Disorder of Proteostasis-Mediated Protein Folding and Trafficking Pathways
por: Karatas, Esra, et al.
Publicado: (2020)

Exo70 Subunit of the Exocyst Complex Is Involved in Adhesion-Dependent Trafficking of Caveolin-1
por: Hertzog, Maud, et al.
Publicado: (2012)

Substrate Stiffness-Driven Membrane Tension Modulates Vesicular Trafficking via Caveolin-1
por: Lachowski, Dariusz, et al.
Publicado: (2022)

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation
por: Plate, Lars, et al.
Publicado: (2016)

Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis
por: Khodaparast, Ladan, et al.
Publicado: (2018)

Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases
por: Cascella, Roberta, et al.
Publicado: (2019)

Cell surface protein aggregation triggers endocytosis to maintain plasma membrane proteostasis
por: Paul, David, et al.
Publicado: (2023)

Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice
por: Sala-Vila, Aleix, et al.
Publicado: (2016)

Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis
por: Chaudhary, Natasha, et al.
Publicado: (2014)

Characterization of the Oligomerization and Aggregation of Human Serum Amyloid A
por: Patke, Sanket, et al.
Publicado: (2013)

The Status of p53 Oligomeric and Aggregation States in Cancer
por: de Oliveira, Guilherme A. P., et al.
Publicado: (2020)

Correction: Exo70 Subunit of the Exocyst Complex Is Involved in Adhesion-Dependent Trafficking of Caveolin-1
por: Hertzog, Maud, et al.
Publicado: (2013)

HIV inhibits endothelial reverse cholesterol transport through impacting subcellular Caveolin-1 trafficking
por: Lin, Shanshan, et al.
Publicado: (2015)

Intracellular Trafficking Pathways of Edwardsiella tarda: From Clathrin- and Caveolin-Mediated Endocytosis to Endosome and Lysosome
por: Sui, Zhi-hai, et al.
Publicado: (2017)

A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production
por: Gautier-Stein, Amandine, et al.
Publicado: (2023)

Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning
por: Shikanai, Mima, et al.
Publicado: (2023)

Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans
por: Calculli, Giuseppe, et al.
Publicado: (2021)

Selective Degradation Permits a Feedback Loop Controlling Annexin A6 and Cholesterol Levels in Endolysosomes of NPC1 Mutant Cells
por: Meneses-Salas, Elsa, et al.
Publicado: (2020)

Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_a2d5lp5ovb904glasic2gdct30